American Idol Reveals Its Top 10 Women






American Idol










02/27/2013 at 10:45 PM EST







From left: Randy Jackson, Mariah Carey, Ryan Seacrest, Nicki Minaj, Keith Urban


Michael Becker/FOX


American Idol's's list of the top 10 women is complete!

After the first week of sudden-death rounds, the judges gave their stamp of approval to five more female singers Wednesday night. And they sent five others home.

Keep reading to find out who's in and who's out on Idol ...

Here are the five contestants who are moving on in the competition:

1. Zoanette Johnson: The Tulsa resident, 20, was the first to be put through by the judges, who showered her with praise for singing a spirited version of "Circle of Life" from The Lion King. Keith Urban declared her "queen of the jungle." Nicki Minaj told Zoanette, "You make me so emotional ... You're the person we're going to remember tonight."

2. Aubrey Cleland: After singing a slowed-down version of Beyoncé's "Sweet Dreams," Mariah Carey told Cleland, 19, "You're limitless." Nicki and Randy Jackson pointed out her commercial appeal. "Lookin' like a current artist, soundin' like one, feelin' like one," said Nicki of the performance.

3. Candice Glover: Taking on Aretha Franklin's "(You Make Me Feel Like) A Natural Woman" paid off for the singer, 23, who earned a standing ovation from Keith. Randy said she was "one of my favorite singers in the whole competition."

4. Breanna Steer: "You're extremely marketable and gorgeous and talented," Mariah told the singer, 18, after she sang a dramatic version of Jazmine Sullivan's "Bust Your Windows" that had Randy wanting to sign her up for a recording contract. "You got the whole package," he said. "You brought so much drama."

5. Janelle Arthur: She beat out the other country singer in the competition, Rachel Hale, for the final spot in the women's top 10 after singing Lady Antebellum's "Just a Kiss." Though Randy called Arthur, 23, his "favorite country singer in this competition," the other judges questioned her song choice. "[The song] doesn't give you a chance to really soar," Keith said. "The melody kept pulling you back."

These five will join the five female finalists announced last week – Kree Harrison, Amber Holcomb, Adriana Latonio, Angela Miller and Tenna Torres – as well as the five men – Charlie Askew, Curtis Finch Jr., Paul Jolley, Elijah Liu and Devin Velez. Ten more guys will sing Thursday (8 p.m. ET) and five will move on to round out season 12's top 20.

Did the judges make the right decisions? Sound off in the comments below.

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India Ink: A Difficult Budget Balancing Act for India

India’s fiscal budget will be announced on Thursday amid slowing economic growth, soaring inflation, a growing fiscal deficit and flagging investor confidence. But with national elections only a year away, analysts fear that instead of cutting the deficit, the government will buckle under political pressure and increase spending on social programs.

“As the country is going into an election period, there is a tendency to try to create a feel-good factor amongst the electorate by enhancing access to welfare schemes and income growth for the masses,” said Sujan Hajra, chief economist and executive director at Anand Rathi Financial Services.

The government has been under pressure to rein in spending as ratings agencies have warned that a failure to cut the deficit could result in a crippling downgrade to India’s sovereign debt.

“The need of the hour is a growth-supportive budget that reinforces reform initiatives and minimizes populist impulses that may act as a drain on the already stretched fiscal condition and raise a red flag for the ever-watchful rating agencies,” said Ajay Bodke, the head of investment strategy and advisory at Prabhudas Lilladher, a Mumbai brokerage.

India’s economy has slowed considerably in recent quarters. On Feb. 7, advance estimates released by India’s Central Statistics Office pegged the growth rate for the current fiscal year, which ends in March, at 5 percent, a significant drop from the central bank’s earlier projections of 5.5 percent and 5.8 percent, and down from over 8 percent in 2010.

In the second quarter of this financial year, the current account deficit reached a record high of $22.4 billion, or 5.4 percent of the gross domestic product, according to data released by the Reserve Bank of India in December.

Prime Minister Manmohan Singh attributed the slowdown to outside forces. “We are meeting against the background of global slowdown of economic activity which has also affected us,” he said in Parliament on Feb. 21. “The way we conduct the financial business now before Parliament will be a crucial determinant of our country’s ability to cope with the formidable challenges that our country faces.”

The government has introduced a series of measures to narrow the deficit, including a rise in passenger rail fares, an increase in fuel prices and the opening of the aviation and retail sectors for foreign direct investment.

Reducing the fiscal deficit has been a priority for the government in recent months. In October, India’s finance minister, Palaniappan Chidambaram, presented a plan  aimed at reducing the fiscal deficit over the next five years, which included a significant reduction in subsidies and tight controls on government expenditure.

In an interview with The Financial Times in January while in England to promote India to investors, Mr. Chidambaram said that the coming budget would be “responsible,” adding, “The red lines are that the fiscal deficit for the current year will be no more than 5.3 percent and the fiscal deficit for the next year will be no more than 4.8 percent.”

Additional measures to overhaul the economy are necessary to reach that target, analysts said. The government is likely to rely on a mix of revenue and spending measures, including proceeds from the divestment of state-run companies and telecom spectrum sales, an increase in indirect taxes and improved tax administration, predicted Leif Lybecker Eskesen, the chief economist for India at HSBC Global Research.

“Debt dynamics depend importantly on broader structural reforms progress, which is needed to raise the economy’s growth potential,” he said. “It is, therefore, imperative to continue and step up the reform push.”

What worries analysts in particular is the National Food Security Bill 2011, which aims to lower the cost of food for the poor.

“If the bill is passed by Parliament, the total food subsidy expense alone would be approximately $14.6 billion per year, or 12 percent of the annual budget,” said Akshay Mathur, head of research at Gateway House, a research institution in Mumbai. Total subsidy expenses, including fuel and fertilizer would be almost 20 percent of the budget, he added.

Critics of the bill argue that the legislation is being introduced with the sole intention of garnering votes for the Congress party in the national elections in 2014.

“There is definitely a political impetus behind the Food Security Bill, but the need is not only a political one,” said Mr. Mathur. “However, the question is how we can pay for it. At this point, given that we have a fiscal deficit and a current account deficit, any added expenditure is a pure drain on the government.”

Meanwhile, fear of a sovereign ratings downgrade by international credit rating agencies is haunting the government. “Rating agencies are also closely watching out for any further fiscal slippage,” said Dipen Shah, head of private client group research at Kotak Securities.

Ratings agencies are looking to the budget for signs of the Indian government’s commitment to fiscal consolidation and structural reform.

“The Union budget will be an important gauge of the government’s commitment to fiscal consolidation and reform in general,” said a report by Fitch Ratings on Feb. 4. “India’s patchy performance on policy implementation, and the approach of elections in 2014 could impede fiscal consolidation, suggesting political and implementation risk remain significant.”

Lalit Thakkar, a managing director at Angel Broking, said that perhaps the ratings agencies’ scrutiny will compel the government to act responsibly.

“We believe that the government cannot afford any adverse economic developments at this juncture on the back of the still-looming threat of sovereign ratings downgrade by credit rating agencies,” he said.

Given that a ratings downgrade from the lowest investment grade to junk status could significantly hamper capital flow, have an adverse impact on the currency, business confidence and the availability of international finance for the corporate sector, perhaps it is this threat that will prove pivotal.

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Bobby Brown Sentenced to 55 Days in Jail in Drunk Driving Case















02/26/2013 at 09:30 PM EST



Bobby Brown has been sentenced to 55 days in jail and four years probation in his most recent drunk driving arrest.

Brown, 44, was pulled over in Studio City, Calif., on Oct. 24 for driving erratically and was arrested when the officer detected "a strong scent of alcohol." He was charged with DUI and driving on a suspended license.

He was also arrested for driving under the influence in March of 2012.

Brown pled no contest to the charges on Tuesday, reports TMZ. He was also ordered to complete an 18-month alcohol treatment program.

The singer, who married Alicia Etheredge in Hawaii in June of 2012, must report to jail by March 20.

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Advanced breast cancer edges up in younger women


CHICAGO (AP) — Advanced breast cancer has increased slightly among young women, a 34-year analysis suggests. The disease is still uncommon among women younger than 40, and the small change has experts scratching their heads about possible reasons.


The results are potentially worrisome because young women's tumors tend to be more aggressive than older women's, and they're much less likely to get routine screening for the disease.


Still, that doesn't explain why there'd be an increase in advanced cases and the researchers and other experts say more work is needed to find answers.


It's likely that the increase has more than one cause, said Dr. Rebecca Johnson, the study's lead author and medical director of a teen and young adult cancer program at Seattle Children's Hospital.


"The change might be due to some sort of modifiable risk factor, like a lifestyle change" or exposure to some sort of cancer-linked substance, she said.


Johnson said the results translate to about 250 advanced cases diagnosed in women younger than 40 in the mid-1970s versus more than 800 in 2009. During those years, the number of women nationwide in that age range went from about 22 million to closer to 30 million — an increase that explains part of the study trend "but definitely not all of it," Johnson said.


Other experts said women delaying pregnancy might be a factor, partly because getting pregnant at an older age might cause an already growing tumor to spread more quickly in response to pregnancy hormones.


Obesity and having at least a drink or two daily have both been linked with breast cancer but research is inconclusive on other possible risk factors, including tobacco and chemicals in the environment. Whether any of these explains the slight increase in advanced disease in young women is unknown.


There was no increase in cancer at other stages in young women. There also was no increase in advanced disease among women older than 40.


Overall U.S. breast cancer rates have mostly fallen in more recent years, although there are signs they may have plateaued.


Some 17 years ago, Johnson was diagnosed with early-stage breast cancer at age 27, and that influenced her career choice to focus on the disease in younger women.


"Young women and their doctors need to understand that it can happen in young women," and get checked if symptoms appear, said Johnson, now 44. "People shouldn't just watch and wait."


The authors reviewed a U.S. government database of cancer cases from 1976 to 2009. They found that among women aged 25 to 39, breast cancer that has spread to distant parts of the body — advanced disease — increased from between 1 and 2 cases per 100,000 women to about 3 cases per 100,000 during that time span.


The study was published Tuesday in the Journal of the American Medical Association.


About one in 8 women will develop breast cancer in their lifetime, but only 1 in 173 will develop it by age 40. Risks increase with age and certain gene variations can raise the odds.


Routine screening with mammograms is recommended for older women but not those younger than 40.


Dr. Len Lichtenfeld, the American Cancer Society's deputy chief medical officer, said the results support anecdotal reports but that there's no reason to start screening all younger women since breast cancer is still so uncommon for them.


He said the study "is solid and interesting and certainly does raise questions as to why this is being observed." One of the most likely reasons is probably related to changes in childbearing practices, he said, adding that the trend "is clearly something to be followed."


Dr. Ann Partridge, chair of the federal Centers for Disease Control and Prevention's advisory committee on breast cancer in young women, agreed but said it's also possible that doctors look harder for advanced disease in younger women than in older patients. More research is needed to make sure the phenomenon is real, said Partridge, director of a program for young women with breast cancer at the Harvard-affiliated Dana-Farber Cancer Institute.


The study shouldn't cause alarm, she said. Still, Partridge said young women should be familiar with their breasts and see the doctor if they notice any lumps or other changes.


Software engineer Stephanie Carson discovered a large breast tumor that had already spread to her lungs; that diagnosis in 2003 was a huge shock.


"I was so clueless," she said. "I was just 29 and that was the last thing on my mind."


Carson, who lives near St. Louis, had a mastectomy, chemotherapy, radiation and other treatments and she frequently has to try new drugs to keep the cancer at bay.


Because most breast cancer is diagnosed in early stages, there's a misconception that women are treated, and then get on with their lives, Carson said. She and her husband had to abandon hopes of having children, and she's on medical leave from her job.


"It changed the complete course of my life," she said. "But it's still a good life."


____


Online:


JAMA: http://jama.ama-assn.org


CDC: http://www.cdc.gov/cancer/breast/index.htm


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IHT Rendezvous: Thank you, Xiexie, Namaste: a Movie Undercuts Old Rivalries

BEIJING — After the Taiwan-born film director Ang Lee won big at the Oscars on Sunday evening in Los Angeles, including scooping Best Director for “Life of Pi,” he effusively thanked his place of birth. But his thanks didn’t make it into China, at least not via the official media.

Why? At almost the same time as Mr. Lee’s speech there was a meeting in Beijing between Xi Jinping, the head of China’s Communist Party, and Lien Chan, the honorary chairman of Taiwan’s Kuomintang party, the latest twist in a political rivalry now dating back 64 years to the end of the Chinese civil war in 1949, when the Kuomintang fled to Taiwan and set up the Republic of China. Communist Party-run China, the People’s Republic of China, still claims Taiwan and has not dropped threats to take it by force, if necessary. Even for Xinhua to quote Mr. Lee thanking Taiwan would be to unacceptably recognize the de facto reality that Taiwan is a separate state.

It’s all deep politics, with Mr. Lee’s victory bound to lead to a debate about whether Mr. Lee is “Chinese or not.” Mr. Lee, who has never denied he is culturally Chinese and appears keen to work in and with the mainland of China, is known to be proud of his Taiwan roots and sees himself as an internationalist.

In its account of the event, Xinhua, the official news agency, merely described him as “Coming from China’s Taiwan”, which fits into China’s ongoing claims.

Here’s what Mr. Lee said about Taiwan: “I cannot make this movie without the help of Taiwan. We shot there. I want to thank everybody there helped us. Especially the city of Tai Chong.” He went on to thank “My family in Taiwan.”

In another story, Xinhua also left out Mr. Lee’s thanks to Taiwan, quoting only this version of his words: “Thank you, movie God. I really need to share this with all 3,000, everybody who worked with me in ‘Life of Pi’, I want to thank you for, I really want to thank you for believing this story, and sharing this incredible journey with me. Thank you, Academy, xie xie, namaste.”

Readers of the Taipei Times, however, learned also that backstage, “Lee thanked his home country, where he said 90 percent of the film was shot. ‘They gave us a lot of physical help and financial help,’ he said. ‘I’m glad that Taiwan contribute this much to the film. I feel like this movie belongs to the world,’” he said in a story carried by the Taiwan newspaper.

As the Taipei Times cited Mr. Lien as saying in the meeting with Mr. Xi, “core issues” remain unresolved. Taiwan and China can work out a reasonable arrangement, Mr. Lian said, according to the newspaper, sounding pragmatic.

Mr. Xi’s had a different, more dramatic take of the situation, speaking of China and Taiwan working together for the “great rejuvenation of the Chinese nation,” in the China Daily’s words, reflecting speeches he has made frequently since becoming party leader.

Meanwhile, Mr. Lee offered something completely different in his speech: a multicultural, multilingual salutation that reflected the deeply globalized nature of his movie, which explores human survival, animals, and religions.

“Thank you, Academy. Xie xie, Namaste,” he said, in English, Mandarin Chinese and Hindi.

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The Bachelor's Sean Lowe Reveals Final Two






The Bachelor










02/25/2013 at 10:30 PM EST







From left: AshLee, Lindsay and Catherine


Kevin Foley/ABC(3)


And then there were two.

After three incredible dates in Thailand with the remaining women, The Bachelor's Sean Lowe faced a difficult decision at the end of Monday's episode: Would he send home AshLee, Catherine or Lindsay?

Keep reading to find out who got a rose – and who was left heartbroken ...

Sean said goodbye to early favorite AshLee in a surprising elimination that left her virtually speechless.

Visibly upset, AshLee left Sean's side without saying goodbye. She even asked him to not walk her to the waiting car that would take her away.

But Sean did get to explain. "I thought it was you from the very beginning," he said. "This was honestly the hardest decision I've ever had to make ... I think the world of you. I did not want to hurt you."

"This wasn't a silly game for me," AshLee said as the car drove away. "This wasn't about a joy ride. It wasn't about laughing and joking and having fun."

She added: "It's hard to say goodbye to Sean because I let him in ... It's the ultimate [rejection]."

Check back Tuesday morning for Sean Lowe's blog post to read all about his Thailand dates and why he chose to send AshLee home

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Koop, who transformed surgeon general post, dies


With his striking beard and starched uniform, former Surgeon General Dr. C. Everett Koop became one of the most recognizable figures of the Reagan era — and one of the most unexpectedly enduring.


His nomination in 1981 met a wall of opposition from women's groups and liberal politicians, who complained President Ronald Reagan selected Koop, a pediatric surgeon and evangelical Christian from Philadelphia, only because of his conservative views, especially his staunch opposition to abortion.


Soon, though, he was a hero to AIDS activists, who chanted "Koop, Koop" at his appearances but booed other officials. And when he left his post in 1989, he left behind a landscape where AIDS was a top research and educational priority, smoking was considered a public health hazard, and access to abortion remained largely intact.


Koop, who turned his once-obscure post into a bully pulpit for seven years during the Reagan and George H.W. Bush administrations and who surprised both ends of the political spectrum by setting aside his conservative personal views on issues such as homosexuality and abortion to keep his focus sharply medical, died Monday at his home in Hanover, N.H. He was 96.


An assistant at Koop's Dartmouth College institute, Susan Wills, confirmed his death but didn't disclose its cause.


Dr. Richard Carmona, who served as surgeon general a decade ago under President George W. Bush, said Koop was a mentor to him and preached the importance of staying true to the science even if it made politicians uncomfortable.


"He set the bar high for all who followed in his footsteps," Carmona said.


Although the surgeon general has no real authority to set government policy, Koop described himself as "the health conscience of the country" and said modestly just before leaving his post that "my only influence was through moral suasion."


A former pipe smoker, Koop carried out a crusade to end smoking in the United States; his goal had been to do so by 2000. He said cigarettes were as addictive as heroin and cocaine. And he shocked his conservative supporters when he endorsed condoms and sex education to stop the spread of AIDS.


Chris Collins, a vice president of amFAR, the Foundation for AIDS Research, said many people don't realize what an important role Koop played in the beginning of the AIDS epidemic.


"At the time, he really changed the national conversation, and he showed real courage in pursuing the duties of his job," Collins said.


Even after leaving office, Koop continued to promote public health causes, from preventing childhood accidents to better training for doctors.


"I will use the written word, the spoken word and whatever I can in the electronic media to deliver health messages to this country as long as people will listen," he promised.


In 1996, he rapped Republican presidential hopeful Bob Dole for suggesting that tobacco was not invariably addictive, saying Dole's comments "either exposed his abysmal lack of knowledge of nicotine addiction or his blind support of the tobacco industry."


Although Koop eventually won wide respect with his blend of old-fashioned values, pragmatism and empathy, his nomination met staunch opposition.


Foes noted that Koop traveled the country in 1979 and 1980 giving speeches that predicted a progression "from liberalized abortion to infanticide to passive euthanasia to active euthanasia, indeed to the very beginnings of the political climate that led to Auschwitz, Dachau and Belsen."


But Koop, a devout Presbyterian, was confirmed after he told a Senate panel he would not use the surgeon general's post to promote his religious ideology. He kept his word.


In 1986, he issued a frank report on AIDS, urging the use of condoms for "safe sex" and advocating sex education as early as third grade.


He also maneuvered around uncooperative Reagan administration officials in 1988 to send an educational AIDS pamphlet to more than 100 million U.S. households, the largest public health mailing ever.


Koop personally opposed homosexuality and believed sex should be saved for marriage. But he insisted that Americans, especially young people, must not die because they were deprived of explicit information about how HIV was transmitted.


Koop further angered conservatives by refusing to issue a report requested by the Reagan White House, saying he could not find enough scientific evidence to determine whether abortion has harmful psychological effects on women.


Koop maintained his personal opposition to abortion, however. After he left office, he told medical students it violated their Hippocratic oath. In 2009, he wrote to Senate Majority Leader Harry Reid, urging that health care legislation include a provision to ensure doctors and medical students would not be forced to perform abortions. The letter briefly set off a security scare because it was hand delivered.


Koop served as chairman of the National Safe Kids Campaign and as an adviser to President Bill Clinton's health care reform plan.


At a congressional hearing in 2007, Koop spoke about political pressure on the surgeon general post. He said Reagan was pressed to fire him every day, but Reagan would not interfere.


Koop, worried that medicine had lost old-fashioned caring and personal relationships between doctors and patients, opened his institute at Dartmouth to teach medical students basic values and ethics. He also was a part-owner of a short-lived venture, drkoop.com, to provide consumer health care information via the Internet.


Koop was born in the New York City borough of Brooklyn, the only son of a Manhattan banker and the nephew of a doctor. He said by age 5 he knew he wanted to be a surgeon and at age 13 he practiced his skills on neighborhood cats.


He attended Dartmouth, where he received the nickname Chick, short for "chicken Koop." It stuck for life.


Koop received his medical degree at Cornell Medical College, choosing pediatric surgery because so few surgeons practiced it.


In 1938, he married Elizabeth Flanagan, the daughter of a Connecticut doctor. They had four children, one of whom died in a mountain climbing accident when he was 20.


Koop was appointed surgeon-in-chief at Children's Hospital in Philadelphia and served as a professor at the University of Pennsylvania School of Medicine.


He pioneered surgery on newborns and successfully separated three sets of conjoined twins. He won national acclaim by reconstructing the chest of a baby born with the heart outside the body.


Although raised as a Baptist, he was drawn to a Presbyterian church near the hospital, where he developed an abiding faith. He began praying at the bedside of his young patients — ignoring the snickers of some of his colleagues.


Koop's wife died in 2007, and he married Cora Hogue in 2010.


He was by far the best-known surgeon general and for decades afterward was still a recognized personality.


"I was walking down the street with him one time" about five years ago, recalled Dr. George Wohlreich, director of the College of Physicians of Philadelphia, a medical society with which Koop had longstanding ties. "People were yelling out, 'There goes Dr. Koop!' You'd have thought he was a rock star."


___


Ring reported from Montpelier, Vt. Cass reported from Washington. AP Medical Writers Lauran Neergaard in Washington and Mike Stobbe in New York contributed to this report.


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India Ink: Forces of Creation Moving in Unison





Presenting non-Western dances to Western audiences can be a difficult business. If an artist adjusts too much, a deep tradition can flatten into pandering tourist fare. If an artist adjusts too little, fidelity can get in the way of communication; a living art form can come across as a relic.







Andrea Mohin/The New York Times

Bijayini Satpathy, left, and Pavithra Reddy of the Nrityagram Dance Ensemble in “Alap.”












A sortable calendar of noteworthy cultural events in the New York region, selected by Times critics.





The Indian choreographer Surupa Sen negotiates the balance with grace. The sinuous, asymmetrical poses of her Odissi tradition, looking at once immovable and full of motion, disguise complex negotiations with gravity as mere embellishments of line. Similarly, Ms. Sen’s choreography elaborates on classical Odissi style while seeming merely to clarify it.


For 20 years Ms. Sen has worked closely with the dancer Bijayini Satpathy. For 20 years, in fact, the two women have lived in the same village in Southern India, Nrityagram, which is devoted to dance. The concert of duets and solos they’re bringing to the Skirball Center (April 6 to 7) is titled “Samyoga,” which in Sanskrit means “union” or “the conjunction of heavenly bodies.” That’s a fair description of Ms. Sen and Ms. Satpathy dancing together.


There’s a philosophical idea behind the work — the interaction between male and female principles in creation — but it can be appreciated on purely aesthetic and theatrical grounds. The women dance both male and female roles. Suggestions of demons and giant birds blend into abstract shapes, patterns and rhythms. A love spat between gods is presented as human comedy, in motion touched by the divine. And, as at all events presented by the World Music Institute, the live music should be at least as distinguished as the dancing.


Souleymane Badolo takes on the translation challenge from a different angle. Born in Burkina Faso, he started his dancing career there, in a traditional African troupe. Since 1993 he has been experimenting with Western contemporary dance, performing in Africa and Europe, but the first work he presented in New York, after he moved there in 2009, still looked pretty foreign. Telling his story in a mixture of French and his native language, Gurunsi, Mr. Badolo enacted a private ritual, slapping his flesh and clicking his tongue.


Since then it’s been fascinating to watch him adapt to his new home. Working with Reggie Wilson, a New York postmodern choreographer well versed in African dance, Mr. Badolo has become more postmodern and more New York. For his performances at New York Live Arts (April 25 to 27) he’s looking again at legacy, the line from his great-great-grandfather to his son. He’s also creating a piece based on a Gurunsi divination method involving the scattering of cowrie seeds.


Is that so different from Merce Cunningham’s chance practices? Is there such a great distance between Africa and downtown New York?


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All the Details on Michelle Obama's Oscar Look







Style News Now





02/25/2013 at 12:50 AM ET











Michelle Obama Oscars Gown
Mario Anzuoni/Reuters/Landov


She was one of the few Oscars guests who didn’t sing a tune, dance a few steps or clutch a trophy, but Michelle Obama‘s surprise appearance during Sunday night’s awards show was still one of the most talked-about moments of the broadcast.


The First Lady appeared via video to announce the Best Picture Oscar, looking like she belonged on the Oscars’ Best Dressed List in a glittering custom smoke gray Naeem Khan gown and Sutra Silver at Fragments jewelry. She wore her bangs straight down but pulled the rest of her hair back into a low bun.


Though it would have made our night if she had gotten dressed to the nines just to present the award from the White House, Obama actually was taking a quick break from hosting the Governors Dinner — so no word on what she thought of the Les MisĂ©rables performance or Seth MacFarlane’s hosting job.


Tell us: Were you surprised to see Michelle Obama? What did you think of her outfit?


–Alex Apatoff


PHOTOS: SEE MORE FABULOUS OSCAR STYLE HERE!




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FDA approves new targeted breast cancer drug


WASHINGTON (AP) — The Food and Drug Administration has approved a first-of-a-kind breast cancer medication that targets tumor cells while sparing healthy ones.


The drug Kadcyla from Roche combines the established drug Herceptin with a powerful chemotherapy drug and a third chemical linking the medicines together. The chemical keeps the cocktail intact until it binds to a cancer cell, delivering a potent dose of anti-tumor poison.


Cancer researchers say the drug is an important step forward because it delivers more medication while reducing the unpleasant side effects of chemotherapy.


"This antibody goes seeking out the tumor cells, gets internalized and then explodes them from within. So it's very kind and gentle on the patients — there's no hair loss, no nausea, no vomiting," said Dr. Melody Cobleigh of Rush University Medical Center. "It's a revolutionary way of treating cancer."


Cobleigh helped conduct the key studies of the drug at the Chicago facility.


The FDA approved the new treatment for about 20 percent of breast cancer patients with a form of the disease that is typically more aggressive and less responsive to hormone therapy. These patients have tumors that overproduce a protein known as HER-2. Breast cancer is the second most deadly form of cancer in U.S. women, and is expected to kill more than 39,000 Americans this year, according to the National Cancer Institute.


The approval will help Roche's Genentech unit build on the blockbuster success of Herceptin, which has long dominated the breast cancer marketplace. The drug had sales of roughly $6 billion last year.


Genentech said Friday that Kadcyla will cost $9,800 per month, compared to $4,500 per month for regular Herceptin. The company estimates a full course of Kadcyla, about nine months of medicine, will cost $94,000.


FDA scientists said they approved the drug based on company studies showing Kadcyla delayed the progression of breast cancer by several months. Researchers reported last year that patients treated with the drug lived 9.6 months before death or the spread of their disease, compared with a little more than six months for patients treated with two other standard drugs, Tykerb and Xeloda.


Overall, patients taking Kadcyla lived about 2.6 years, compared with 2 years for patients taking the other drugs.


FDA specifically approved the drug for patients with advanced breast cancer who have already been treated with Herceptin and taxane, a widely used chemotherapy drug. Doctors are not required to follow FDA prescribing guidelines, and cancer researchers say the drug could have great potential in patients with earlier forms of breast cancer


Kadcyla will carry a boxed warning, the most severe type, alerting doctors and patients that the drug can cause liver toxicity, heart problems and potentially death. The drug can also cause severe birth defects and should not be used by pregnant women.


Kadcyla was developed by South San Francisco-based Genentech using drug-binding technology licensed from Waltham, Mass.-based ImmunoGen. The company developed the chemical that keeps the drug cocktail together and is scheduled to receive a $10.5 million payment from Genentech on the FDA decision. The company will also receive additional royalties on the drug's sales.


Shares of ImmunoGen Inc. rose 2 cents to $14.32 in afternoon trading. The stock has ttraded in a 52-wek range of $10.85 to $18.10.


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